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Inundated With Data: The "-OMICS"
Problem
Organized by: Karin D. Rodland, Pacific Northwest
National Laboratory and Valda Vinson, AAAS Science
magazine
Saturday, 19 February 2005
8:00AM–3:30PM
Sponsored by Pacific Northwest National Laboratory
High-throughput biology -- the newest technical trend
in the life sciences -- has as much potential to change
research as the recombinant biology revolution of the
1970s and 1980s. The "-omics" explosion simply
reflects the capturing of data on all the different
molecules that can now be measured accurately and rapidly:
genes, mRNA, proteins, metabolites, sugars, lipids,
and more. But what do you do with all these data once
you have them? Technological challenges exist around
determining the quality of the data, storing and transmitting
them, and integrating data types. But even more important
are the practical issues that are at the heart of systems
biology. What new insights do these large data sets
provide? Will we ever know completely the workings of
a single cell, let alone predict its response to change?
High-throughput biology provides the tools needed to
unlock the answers to these questions. This seminar
will explore critical issues and questions.
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SATURDAY • 19 February
2005 • Marriott Wardman Park, Mezzanine Level,
Wilson C
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| 8:00AM–9:30AM |
What is High-Throughput Biology?
• Steve Wiley, Pacific Northwest National
Laboratory
The -OMICS Revolution: How Many Different Things
Can You Measure?
• Michael Snyder, Yale University
High Throughput Approaches to Understanding
the Genome
• George Michaels, Pacific Northwest National
Labs
Bioinformatics: Making Sense of the Flood of
Proteomic Data
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| 9:45AM–11:15AM |
From Genes to Proteins
• Fabio Piano, New York University
Defining Functional Genomics
• Joseph R. Nevins, Duke University
Transcriptional Profiling and Understanding
Cancer
• Leigh Anderson, Plasma Proteome Institute
Proteomics as a Tool for Clinical Diagnostics
• Mark Gerstein, Yale University
Putting It All Together: Integrating the Data
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| 2:00PM–3:30PM |
Beyond the Central Dogma
• Jeremy Nicholson, Imperial College
Metabonomics: What Are Those Other Small Molecules
Doing?
• Jack Greenblatt, University of Toronto
Attractive Relationships: The Interactome
• Trey Ideker, University of California,
San Diego
Visualizing Networks from Interaction Data
• Douglas A. Lauffenberger, Massachusetts
Institute of Technology
To Be or Not to Be? Cell Life and Death Decisions
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