A Practicum
June 4-5, 2000
St. Charles, IL

Convened by
American Association for the Advancement of Science
U.S. Office of Research Integrity

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SPEAKER BIOGRAPHIES

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Mark Brenner earned his Ph.D. in Horticulture at Michigan State University in 1970. As a member of the faculty at the University of Minnesota from 1969-1998, he taught Horticultural Science and Plant Biology and served in various administrative roles. These roles included Associate Dean of the Graduate School, Associate Vice President for Research, and Vice President for Research and Dean of the Graduate School.

Dr. Brenner left Minnesota in 1998 to become the Vice Chancellor for Research and Graduate Education at Indiana University Purdue University Indianapolis (IUPUI) and Associate Vice President for Research, Indiana University. In this new position, he is leading efforts to promote the creation of graduate certificate programs and new master's and Ph.D. programs, strengthen interdisciplinary research and graduate education, and develop an electronic research administration system. As part of the research administration system, he is implementing a comprehensive educational program on responsible conduct in research.

Throughout his academic career, Dr. Brenner has accumulated over 80 publications, as well as numerous honors and awards that have recognized his outstanding contributions to the field of Horticultural Science, to graduate and professional education, and to service to Agriculture and the related sciences and arts. He is also active in several professional organizations. In addition to serving on the editorial board of the Council of Graduate Schools, he is a member of the Executive Committee of the Midwest Association of Graduate Schools, Executive Committee of the Council for Research Policy and Graduate Education of the National Association of State Universities and Land Grant Colleges, and the Research Compliance and Administration Committee of the Council on Governmental Relations.

James F. Burris, M.D., is the Deputy Chief Research and Development Officer for the Veterans Health Administration, U.S. Department of Veterans Affairs. He is also a Clinical Professor of Medicine and Pharmacology at Georgetown University School of Medicine.

Dr. Burris is a graduate of Brown University and of the College of Physicians and Surgeons of Columbia University. He served his medical internship at Roosevelt Hospital in New York City and completed his medical residency at Georgetown. He was a Hypertension Research Fellow with Dr. Edward Freis at the Washington VA Medical Center and a Visiting Investigator with Dr. Hans Brunner at the Central University Hospital in Lausanne, Switzerland. He is Board-certified in Internal Medicine, Geriatrics, and Clinical Pharmacology.

Dr. Burris is the author of more than 200 scientific papers, book chapters, case reports and abstracts reporting his clinical research in hypertension and hyperlipidemia. He is a Fellow of several professional societies, including the American College of Physicians, the American College of Cardiology, the American Geriatrics Society, the American College of Clinical Pharmacology, and the American College of Preventive Medicine.

As Associate Dean for Research Operations at Georgetown University from 1987-97, Dr. Burris was responsible for oversight of conflict of interest and scientific misconduct issues, the Institutional Review Board, and the Environmental Health and Safety Office (radiation, biologic, and chemical hazards). He has assumed a similar risk management portfolio for VA Research and Development. He previously served as a member of the Committee on Research Integrity for the Association of American Medical Colleges. He is currently a member of the Washington Area Consortium on Research Integrity and of the Ethics Committee of the American Society for Clinical Pharmacology and Therapeutics.

David Clark earned a Ph.D. in Psychology from the University of Chicago and is a licensed clinical psychologist. His current academic position is Stanley G. Harris Family Professor of Psychiatry at Rush Medical College. His current administrative position is Director and Assistant Vice President, Office of Research Affairs at Rush-Presbyterian-St. Luke's Medical Center. He has been on the Rush faculty since 1974. Dr. Clark's funded and published research has focused in the areas of mood and anxiety disorders, evaluating and treating suicidal persons, and the psychosocial development of medical professionals. He was awarded the Edwin Shneidman Award for outstanding contributions in research to suicidology by the American Association of Suicidology. He is a member of the International Academy for Suicide Research and recently served as Secretary-General of the International Association for Suicide Prevention. Dr. Clark is editor of a half-dozen national and international scientific journals on suicide prevention.

Margaret L. Dale, J.D., is Associate Dean for Faculty Affairs and Director of the Office for Research Issues at Harvard Medical School. She received an A.B. degree from Middlebury College in 1968 and a J.D. degree from Boston University in 1976. Prior to coming to Harvard in 1991, Ms. Dale served as Deputy General Counsel for the Massachusetts Commission Against Discrimination and as General Counsel for the Massachusetts Department of Personnel Administration. Ms. Dale's areas of responsibility at Harvard Medical School include scientific misconduct, conflict of interest, senior faculty appointments, faculty retirement, invitational faculty fellowships and prizes, and other faculty related matters.

Alicia Dustira is Deputy Director of the Division of Policy and Education in the Office of Research Integrity (ORI) of the U.S. Department of Health and Human Services, where she is responsible for the development of various educational programs designed to identify and prevent research misconduct. Before joining ORI in 1993, she served as Executive Secretary for the President's Council of Advisors on Science and Technology in the Office of Science and Technology Policy (OSTP) within the Executive Office of the President and as Senior Policy Analyst for Life Sciences. While at OSTP, she was responsible for obtaining final agency approval for the Federal Common Rule for the Protection of Human Research Subjects. Dr. Dustira directed a study for the Institute of Medicine of the National Academy of Sciences concerning the allocation of U.S. biomedical research funding from 1988-1990, and served as programs officer for Sigma Xi, The Scientific Research Society from 1984-1988. While at Sigma Xi headquarters, she produced a nationwide teleconference on the greenhouse effect, directed an investigation of multidisciplinary approaches to research, as well as advising the Smithsonian Institution on a nationwide teleconference on biological diversity. Dr. Dustira is a former member of the AAAS-ABA National Conference of Lawyers and Scientists and the Maryland Biotechnology Institute Advisory Board. Dr. Dustira also had done research and published articles on her work in animal behavior, immunogenetics, and immunology while at Rutgers University, the University of Pennsylvania School of Medicine, and Baylor College of Medicine. A graduate of Smith College, Dr. Dustira received an M.S. in animal behavior and a Ph.D. in immunogenetics from Rutgers University, New Brunswick, New Jersey.

 

 

Caroline joined ORI as Chief Counsel in October, 1999. As Chief Counsel, she oversees ORI's legal operations which include representing the office in administrative hearings before the Departmental Appeals Board, drafting regulatory and legislative initiatives, and providing advice and counsel to ORI's oversight and education divisions. Caroline received her B.A. from Princeton University in 1984, and her law degree from George Washington in 1988. After law school, she became an associate with the law firm of Linowes and Blocher where she represented nonprofit healthcare and educational institutions in loan and real estate transactions. In 1991, Caroline joined the Office of Constitutional and Specialized Torts, U.S. Department of Justice, where she served as a trial attorney for 8 years.

John E. Dahlberg, Ph.D., is a senior investigator in the Division of Research Investigations of the Office of Research Integrity. He received a B.A. from Brandeis University in 1963 and a Ph.D. in microbiology from Purdue University in 1968. After post-doctoral fellowships at the Public Health Research Institute of the City of New York and at Rutgers University, he spent sixteen years at the National Cancer Institute in Bethesda carrying out research on retroviruses with an initial emphasis on ultrastructure and virus classification. Subsequently he focused increasingly on immunoassay development and molecular biology and, using all of these technologies, began research on lentiviruses in 1980. In 1988, Dr. Dahlberg joined a small biotechnology company as director of research and development, where he developed procedures for growing macrophage cells in serum-free medium and using them to test drugs for their ability to inhibit HIV replication. Dr. Dahlberg joined the Office of Scientific Integrity in 1992, just prior to its being reorganized into ORI. While at ORI, he has developed a variety of computer-aided techniques to assist

Peggy Fischer is the Associate Inspector General for Scientific Integrity in the Office of Inspector General at the National Science Foundation. She is responsible for the management and resolution of all allegations of wrongdoing, including misconduct in science, involving NSF activities. In that position, she works closely with NSF grantees and other government agencies to resolve allegations. She also directs the Office's Outreach Program which is designed to develop and improve the Office's partnerships with institutions, NSF, and members of the scientific community. In previous positions in the Office of Inspector General she worked to resolve allegations of misconduct in science and planned and conducted inspections at grantee institutions and programmatic reviews within NSF.

Prior to coming to NSF, Dr. Fischer served as a senior program officer for the National Research Council's Board on Biology. She principally worked on the Funding of Young Investigators project (resulting in an NRC publication), as well as on biodiversity and conservation issues. Before coming to the NRC, she was the Director of Research and Development (national and international operations) for Flow Laboratories, a biotechnology company. She was responsible for the development of new products ranging from computerized instrumentation to cell culture products, quality control and assurance procedure development, and bioreactor product line marketing.

Dr. Fischer did her postdoctoral research at the National Cancer Institute and the University of Connecticut Health Center. Her research focused on understanding the structure and expression of particular structural and hormone-responsive genes. She received her Ph.D. in cell biology with a molecular emphasis at the University of Connecticut, and her BS in Zoology from North Carolina State University.

Mark S. Frankel, Ph.D., has been director of the Scientific Freedom, Responsibility and Law Program at the American Association for the Advancement of Science since 1990 where he develops and manages the Association's activities related to professional ethics, science and society, and science and law. He is staff officer for two AAAS committees--the Committee on Scientific Freedom and Responsibility and the AAAS-American Bar Association National Conference of Lawyers and Scientists--and editor of the Association's quarterly publication, Professional Ethics Report. He has directed several AAAS projects on research integrity and scientific misconduct, and is a Fellow of AAAS.

Rachel J. Gray received her B.A in Law with Honours in 1997 from Carleton University, Ottawa, Canada, and her M.A in Biomedical Ethics in 1998 from Case Western Reserve University, Cleveland, Ohio. She joined the American Association for the Advancement of Science in 1998 where she currently serves as Program Associate for the Scientific Freedom, Responsibility and Law Program. Ms. Gray is a contributing editor to the the Professional Ethis Report. Her areas of interest include research ethics, genetic engineering and intellectual property law.

John Krueger is an Investigator-Scientist in the Division of Research Investigations, ORI. He obtained a Ph.D. in Biomedical Engineering from Iowa State University, with postdoctoral training at Imperial College London, and the University of Washington. Prior to joining ORI, he was a senior faculty member at the Albert Einstein College of Medicine, where he was the Wunsch Fellow in Biophysical Engineering and an Established Fellow of the New York Heart Association. Dr. Krueger's research publications involve the contractile physiology and biophysics of the cardiac sarcomere and single cardiac cell, and he is the inventor on two patents on micromanipulators. His interests at ORI involve image processing methods for the forensic examination of questioned images and data.

Ms. Mishkin concentrates on the federal regulation of biomedical research, particularly scientific misconduct, university/industry relations, research involving human subjects, and grants administration. Her clients are primarily universities, medical schools, and research institutions. Ms. Mishkin also is experienced in the rights of patients to privacy, confidentiality, and control over their health care.

Prior to joining Hogan & Hartson in 1983, Ms. Mishkin served as Deputy Director of the President's Commission for the Study of Ethical Problems in Medicine and Biomedical and Behavioral Research from 1980-83. Ms. Mishkin's previous positions at the U.S. Department of Health, Education, and Welfare included: Staff Director, HEW Ethics Advisory Board; Assistant Staff Director, National Commission for the Protection of Human Subjects; and Research Psychologist, Section on Neuropsychology, National Institute of Mental Health. Ms. Mishkin has also served as Special Assistant for Health Sciences to the Honorable David L. Bazelon (then, Chief Judge, U.S. Court of Appeals, D.C. Circuit).

Ms. Mishkin has written and lectured extensively on the regulation of biomedical research, scientific misconduct, and biomedical ethics, and is a frequent consultant to the federal government on legislative and regulatory issues. Her present and past activities include: Chair, ABA Committee on Regulating Research, ABA Co-Chair, National Conference of Lawyers and Scientists; Fellow, American Association for the Advancement of Science (AAAS); Advisory Committee, AAAS Program on Scientific Freedom and Responsibility; Member AAAS/ABA Conference of Lawyers and Scientists; contributing editor, AAAS Professional Ethics Report; Trustee of Mount Holyoke College; Board of Managers, Bon Secours Health System, Inc.; Board, Hebrew Home of Greater Washington; Vice-Chair, Legal Counsel for the Elderly; and Chair, Committee on Health and Environmental Rights, ABA Section on Individual Rights and Responsibilities.

Ms. Mishkin was named Pro Bono Attorney of the Year (1988) by the District of Columbia Bar, for her representation of patients unable to make health care decisions and her work with Legal Counsel for the Elderly.

Chris B. Pascal, J.D. Mr. Pascal currently holds the position of Acting Director, Office of Research Integrity, within the Office of Public Health and Science at the Department of Health and Human Services, Rockville, Maryland.

Mr. Pascal began his government career over 20 years ago by working as Chief Counsel for the Alcohol, Drug Abuse, and Mental Health Administration within the U.S. Department of Health and Human Services. After 15 years, he became Chief Counsel for the Office of Research Integrity within the U.S. Public Health Service, moving on three years later to become Director of the Division of Research Investigations. Shortly thereafter, Mr. Pascal assumed his present position.

Mr. Pascal took his baccalaureate degree at Auburn University and his J.D. degree at Duke University School of Law. He did a postdoctoral fellowship in psychology and law in the Psychiatry Department at Duke University Medical Center.

Dr. Price earned his B.S. in Chemistry from Florida State University in 1964, and his Ph.D. in Biochemistry from the University of Minnesota in 1968, after which he was a postdoctoral fellow in Biochemistry through 1969 at Michigan State University.

In 1970, Dr. Price joined the faculty of the University of Michigan Medical School, where he did taught and did research, becoming Associate Professor of Biological Chemistry with tenure. His research dealt with the enzymology of nucleotide and DNA synthesis in unusual bacterial viruses.

In 1978, Dr. Price added research administration to his duties, becoming Assistant Dean for Research in the Medical School. In 1981, he was appointed Assistant Vice President for Research for the University of Michigan.

In 1987, Dr. Price decided to gain experience in Federal research administration, moving to the National Institutes of Health (NIH) in Maryland. He was the Program Officer for genetics grants for the National Institute of Aging for one year. Then he became the AIDS Unit Assurance Coordinator in the Office for Protection from Research Risks, responsible for protection of human subjects in all Public Health Service (PHS) grants on AIDS research.

In 1990, Dr. Price became a Senior Scientist in the new Office of Scientific Integrity (OSI) at the NIH, now the Office of Research Integrity (ORI) at the PHS. He has had responsibilities for supervising scientific and professional staff, conducting investigations, approving institutional investigative reports, and developing national policies for PHS grants as they relate to research integrity. He also has presented many seminars and conducted educational workshops on dealing with research misconduct and maintaining integrity in biomedical research. He was promoted in 1991 to OSI Assistant Director. When OSI became ORI in1992, he served as Chief of the Investigations Branch. In 1999, he was promoted to Acting Director of ORI's Division of Research Investigations.