Skip to main content

Life sciences/Biochemistry/Protein functions/Protein activation

A new study confirms that the human sirtuin protein known as SIRT1, which has been shown to combat age-related diseases in many animals, can be directly activated by resveratrol—a natural compound found in the skin of grapes used to make red wine. Resveratrol is one of many so-called sirtuin-activating compounds, or STACs.

Two mouse studies published this week suggest innovative approaches for treating two of the developed world’s most troubling diseases. One study tests a potential therapy using an FDA-approved cancer drug to treat Alzheimer’s, while the other examines how a few days of fasting may delay tumor growth and improve chemotherapy.