Gene therapy can be used to transform some of a pig's regular heart cells into pacemaker cells, according to a new study in Science Translational Medicine.

Oil compounds interfere with cellular signals needed for a healthy heartbeat in fish, a new study suggests.

A new study in dogs reveals two genes responsible for controlling heartbeat rhythm and re-coordinating the action of the heart’s right and left ventricles. These genes may be part of the molecular pathway affected by pacemakers, researchers report in the 14 September issue of the journal Science Translational Medicine.

Using gene therapy or drugs to activate these genes in heart failure patients may help people who cannot use a pacemaker—or possibly replace pacemakers altogether, the study authors propose.