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Life sciences/Organismal biology/Anatomy/Digestive system/Pancreas

Researchers have developed antibodies that fight high blood sugar in mice, according to a new study in the 14 December issue of the journal Science Translational Medicine. These proteins could potentially be used to develop new drugs for type 2 diabetes, a condition that develops when the pancreas stops making insulin or when the body stops responding to insulin.

Weight loss by gastric bypass surgery alters the metabolism of individuals in ways that are different from the effects of dieting, reports a new study in the 27 April issue of Science Translational Medicine. The results are preliminary but could help researchers find new ways to treat diabetes.

“The rapid reversal of diabetes after gastric bypass surgery points to mechanisms other than weight loss involved in improved glucose levels,” said lead author Blandine Laferrère, assistant professor in medicine at Columbia University College of Physicians and Surgeons.

An artificial pancreas that uses a computer algorithm to balance sugar levels in the body could help patients with type 1 diabetes better control the disease, reports a new study in Science Translational Medicine.