Cryo–electron tomograph inside a yeast cell (blue, ribosomes; yellow, genetically encoded nanoparticle; gray, organelle membranes). This technique is used to resolve macromolecular structure and spatial organization in the native cellular environment with single-molecule precision and to study phase separation. The Gordon Research Conference on Three Dimensional Electron Microscopy will be held from 31 October to 5 November 2021 in Newry, Maine. See page 1230 for the Gordon Research Conference schedule and preliminary programs.
Image: Dimitry Tegunov, Stefan Pfeffer, Jürgen Plitzko, Liam Holt, Benjamin D. Engel