BMENA Case Study - Isolation of avian influenza H5N1 virus from vaccinated commercial layer flock in Egypt

This case study is based on an article that analyzes the effectiveness of the H5N1 poultry vaccination program and vaccines used in Egypt’s national H5N1 surveillance program. This case study has been designed to train participants doing research risk analysis and promote dialogue on the ethical dilemmas and socioeconomic concerns related to H5N1 and other livestock vaccination campaigns, biorisk and safety issues associated with working with highly pathogenic infectious diseases and research animals, and the ethical and security implications of research that has the potential to be useful for both malicious and beneficial purposes (referred to as dual use potential).

The primary risk areas that this case study addresses are:

• Biosecurity and dual use research
• Biosafety and handling isolated H5N1
• Animal subjects safety
• Economic risks and public health risks for misuse or accidental release

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